Comparative analysis of myocardial protection with htk solution and hypothermic hyperkalemic blood solution in the correction of acyanogenic congenital cardiopathies - a randomized study
Rev. bras. cir. cardiovasc
;
34(3): 271-278, Jun. 2019. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1013463
ABSTRACT
Abstract Objective:
The goal of the present study was to compare the myocardial protection obtained with histidine-tryptophan-ketoglutarate (HTK) cardioplegic solution (Custodiol®) and with intermittent hypothermic blood solution.Methods:
Two homogenous groups of 25 children with acyanotic congenital heart disease who underwent total correction with mean aortic clamping time of 60 minutes were evaluated in this randomized study. Troponin and creatine kinase-MB curves, vasoactive-inotropic score, and left ventricular function were obtained by echocardiogram in each group. The values were correlated and presented through graphs and tables after adequate statistical treatment.Results:
It was observed that values of all the studied variables varied over time, but there was no difference between the groups.Conclusion:
We conclude that in patients with acyanotic congenital cardiopathies submitted to total surgical correction, mean aortic clamping time around one hour, and cardiopulmonary bypass with moderate hypothermia, the HTK crystalloid cardioplegic solution offers the same myocardial protection as the cold-blood hyperkalemic cardioplegic solution analyzed, according to the variables considered in our study model.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Soluciones Cardiopléjicas
/
Cardiopatías Congénitas
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio observacional
/
Estudio pronóstico
Límite:
Femenino
/
Humanos
/
Lactante
/
Masculino
/
Recién Nacido
Idioma:
Inglés
Revista:
Rev. bras. cir. cardiovasc
Asunto de la revista:
Cardiología
/
Cirugía General
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Centro Universitário Unichristus/BR
/
Hospital de Messejana Dr. Carlos Alberto Studart Gomes/BR
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