Molecular epidemiology of agents of human chromablastomycosis inBrazil with the description of two novel species
PLOS Neglected tropical diseases
;
11(1): 1-5, 2016. ilus
Artículo
en Inglés
| SES-SP, LILACS, SESSP-IALPROD, SES-SP, SESSP-IALACERVO
| ID: biblio-1021882
ABSTRACT
The human mutilating disease chromoblastomycosis is caused by melanized members of the order Chaetothyriales. To assess population diversity among 123 clinical strains of agents of the disease in Brazil we applied sequencing of the rDNA internal transcribed spacer region, and partial cell division cycle and ß-tubulin genes. Strains studied were limited to three clusters divided over the single family Herpotrichiellaceae known to comprise agents of the disease. A Fonsecaea cluster contained the most important agents, among which F. pedrosoi was prevalent with 80% of the total set of strains, followed by 13% for F. monophora, 3% for F. nubica, and a single isolate of F. pugnacius. Additional agents, among which two novel species, were located among members of the genus Rhinocladiella and Cyphellophora, with frequencies of 3% and 1%, respectively.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Humanos
/
Enfermedad
/
Cromoblastomicosis
Tipo de estudio:
Estudio de tamizaje
Idioma:
Inglés
Revista:
PLOS Neglected tropical diseases
Año:
2016
Tipo del documento:
Artículo
Institución/País de afiliación:
Universidade Federal do Maranhão/BR
/
Universidade Federal do Paraná/BR
/
Universidade Federal do Pará/BR
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