Intermittent vibrations accelerate fracture healing in sheep
Acta cir. bras
;
34(7): e201900702, 2019. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1038116
ABSTRACT
Abstract Purpose:
To investigate the effect of intermittent vibration at different intervals on bone fracture healing and optimize the vibration interval.Methods:
Ninety sheep were randomized to receive no treatment (the control group), incision only (the sham control group), internal fixation with or without metatarsal fracture (the internal fixation group), and continuous vibration in addition to internal fixation of metatarsal fracture, or intermittent vibration at 1, 2, 3, 5, 7 and 17-day interval in addition to internal fixation of metatarsal fracture (the vibration group). Vibration was done at frequency F=35 Hz, acceleration a=0.25g, 15 min each time 2 weeks after bone fracture. Bone healing was evaluated by micro-CT scan, bone microstructure and mechanical compression of finite element simulation.Results:
Intermittent vibration at 7-day interval significantly improved bone fracture healing grade. However, no significant changes on microstructure parameters and mechanical properties were observed among sheep receiving vibration at different intervals.Conclusions:
Clinical healing effects should be the top concern. Quantitative analyses of bone microstructure and of finite element mechanics on the process of fracture healing need to be further investigated.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Vibración
/
Huesos Metatarsianos
/
Curación de Fractura
/
Fracturas Óseas
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
China
Institución/País de afiliación:
Institute of Medical Equipment/CN
/
the First Hospital of Jilin University/CN
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