The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material - an in vitro study
J. appl. oral sci
;
27: e20180779, 2019. tab, graf
Artículo
en Inglés
| LILACS, BBO
| ID: biblio-1040232
ABSTRACT
Abstract Candida albicans is the main causative pathogen of denture stomatitis, which affects many complete denture patients. Objective:
To evaluate the effect of different concentrations of nanodiamonds (NDs) added to polymethyl methacrylate (PMMA) denture base material on Candida albicans adhesion as well as on surface roughness and contact angle.Methodology:
Acrylic resin specimens sized 10×10×3 mm3 were prepared and divided into four groups (n=30) according to ND concentration (0%, 0.5%, 1%, 1.5% by wt). Surface roughness was measured with a profilometer, and the contact angle with a goniometer. The effect of NDs on Candida albicans adhesion was evaluated using twomethods:
1) slide count and 2) direct culture test. Analysis of variance (ANOVA) and Tukey's post hoc test were used in the statistical analyses.Results:
Addition of NDs decreased the Candida albicans count significantly more than in the control group (p<0.05), with a lowest of 1% NDs. Addition of NDs also significantly decreased the surface roughness (p<0.05), but the contact angle remained the same. Incorporation of NDs into the PMMA denture base material effectively reduced Candida albicans adhesion and decreased surface roughness.Conclusion:
PMMA/NDs composites could be valuable in the prevention of denture stomatitis, which is considered one of the most common clinical problems among removable denture wearers.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Resinas Acrílicas
/
Candida albicans
/
Polimetil Metacrilato
/
Bases para Dentadura
/
Nanodiamantes
Tipo de estudio:
Estudios de evaluación
Límite:
Humanos
Idioma:
Inglés
Revista:
J. appl. oral sci
Asunto de la revista:
Odontología
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Finlandia
/
Arabia Saudita
Institución/País de afiliación:
Imam Abdulrahman Bin Faisal University/SA
/
University of Oulu/FI
/
University of Turku/FI
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