Preliminary assessment of anti-α-Gal IgG and IgM levels in patients with patent Plasmodium vivax infection
Mem. Inst. Oswaldo Cruz
;
114: e190145, 2019. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1040609
ABSTRACT
Anti-α-Gal responses may exert a protective effect in falciparum malaria. However, the biological role of such antibodies is still unknown during Plasmodium vivax infections. We investigated IgG and IgM responses to α-Gal in individuals with vivax malaria. Anti-α-Gal IgG and IgM levels were higher in these patients than in controls, but no significant correlation was found between parasitaemia and anti-α-Gal response, nor between this response and ABO blood group status. This is the first study to investigate anti-α-Gal antibodies in P. vivax-infected patients; a larger survey is necessary to achieve a better understanding of host immune response during vivax malaria.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Plasmodium vivax
/
Inmunoglobulina G
/
Inmunoglobulina M
/
Anticuerpos Antiidiotipos
/
Malaria Vivax
Límite:
Adulto
/
Humanos
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Brasil
/
Estados Unidos
Institución/País de afiliación:
Georgia Institute of Technology/US
/
Universidade Federal de Minas Gerais/BR
/
Universidade Federal do Mato Grosso/BR
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