Evaluation of the commercial kit SIRE nitratase for detecting resistant mycobacterium tuberculosis in Brazil
Rev. Soc. Bras. Med. Trop
;
50(4): 550-553, July-Aug. 2017. tab
Artículo
en Inglés
| LILACS
| ID: biblio-1041420
ABSTRACT
Abstract INTRODUCTION:
This study aimed to evaluate a new commercial kit, Kit SIRE Nitratase-PlastLabor, for testing the drug susceptibility of clinical Mycobacterium tuberculosis isolates.METHODS:
The accuracy of the Kit SIRE Nitratase was evaluated by examining the susceptibility (streptomycin, isoniazid, rifampicin, and ethambutol) of 40 M. tuberculosis isolates, using the proportion method with Lowenstein-Jensen medium or the BACTEC MGIT 960 system.RESULTS:
The detection accuracy for streptomycin, isoniazid, rifampicin, and ethambutol was 95%, 97.5%, 100%, and 80%, respectively.CONCLUSIONS:
The exceptional accuracy demonstrated by Kit SIRE Nitratase for isoniazid and rifampicin makes the kit an attractive option for screening M. tuberculosis strain resistance.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Oxidorreductasas
/
Pruebas de Sensibilidad Microbiana
/
Antibióticos Antituberculosos
/
Mycobacterium tuberculosis
Límite:
Humanos
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2017
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Ministério da Saúde/BR
/
Universidade Federal de Minas Gerais/BR
/
Universidade Federal do Rio de Janeiro/BR
Similares
MEDLINE
...
LILACS
LIS