Alterations induced in the ileum of mice upon inoculation with different species of Leishmania: a preliminary study
Rev. Soc. Bras. Med. Trop
;
51(4): 537-541, July-Aug. 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1041471
ABSTRACT
Abstract INTRODUCTION:
Leishmania species cause skin, mucosal, and disseminated lesions. We studied the effects of three Leishmania species on ileal morphology in mice.METHODS:
BALB/c mice were intraperitoneally inoculated with Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, and Leishmania (Leishmania) major (4 animals/group). After 72h, the ilea were collected and histologically processed.RESULTS:
Following inoculation, the goblet cell and intraepithelial lymphocyte populations increased, while Paneth cell number and crypt width decreased. In addition, enterocyte size, villi height, and mucosa, submucosa, and muscular tunic thickness increased.CONCLUSIONS:
Leishmania modified the quantity of cells in and morphology of mice ilea.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Leishmaniasis
/
Íleon
/
Leishmania
/
Ratones
Límite:
Animales
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Estadual de Maringá/BR
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