Therapeutic failure after regimen with artemether-lumefantrine combination therapy: a report of three cases in Benin City, Nigeria
Rev. Soc. Bras. Med. Trop
;
52: e20190163, 2019.
Artículo
en Inglés
| LILACS
| ID: biblio-1041528
ABSTRACT
Abstract Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization for the treatment of uncomplicated malaria. Currently, there appears to be a downward trend in the efficacy of ACT in some parts of sub-Saharan Africa because some patients have been positive for Plasmodium parasite 3 days after artemether-lumefantrine treatment. We reported three cases of possible parasite resistance to artemether-lumefantrine therapy. All subjects had complete parasite clearance when treated with other antimalarial drugs. This observation necessitates the urgent need to re-evaluate artemether-lumefantrine medication in Nigeria since it is one of the most commonly used ACT drug.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Malaria Falciparum
/
Combinación Arteméter y Lumefantrina
/
Antimaláricos
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Nigeria
Institución/País de afiliación:
Bethel Faith Medical Centre/NG
/
Michael and Cecilia Ibru University/NG
/
University of Benin/NG
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