Emergence of bla NDM-1 associated with the aac(6')-Ib-cr, acrB, cps, and mrkD genes in a clinical isolate of multi-drug resistant Klebsiella pneumoniae from Recife-PE, Brazil
Rev. Soc. Bras. Med. Trop
;
52: e20180352, 2019. tab
Artículo
en Inglés
| LILACS
| ID: biblio-1041560
ABSTRACT
Abstract INTRODUCTION: The emergence of New Delhi metallo-β-lactamase (NDM) is concernig because it reduces the antibiotic therapy options for bacterial infections. METHODS: Resistant and virulent genes from an isolate of Klebsiella pneumoniae derived from a patient with sepsis in a hospital in Recife-PE, Brazil, were investigated using PCR and DNA sequencing. RESULTS: bla NDM-1, aac(6')-Ib-cr and acrB resistance genes, and cps and mrkD virulence genes were detected. CONCLUSIONS To our knowledge, this is the first report on bla NDM-1 in Recife-PE. This detection alerts researchers to the need to control the spread of bla NDM-1 resistance gene by this bacterium in Brazil.
Texto completo:
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Índice:
LILACS (Américas)
Asunto principal:
Proteínas Bacterianas
/
Virulencia
/
Beta-Lactamasas
/
Farmacorresistencia Bacteriana Múltiple
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Klebsiella pneumoniae
/
Antibacterianos
Tipo de estudio:
Factores de riesgo
Límite:
Femenino
/
Humanos
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal de Pernambuco/BR
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