Epidemiological and TNFα polymorphism evaluation in patients with cryptococcal meningitis treated at a referral hospital in North Brazil
Rev. Soc. Bras. Med. Trop
;
52: e20180376, 2019. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1041562
ABSTRACT
Abstract INTRODUCTION:
The present study evaluated the epidemiology of cryptococcal meningitis and TNFα gene polymorphisms in patients at a reference hospital in northern Brazil.METHODS:
Samples from 25 patients infected with Cryptococcus spp. were collected to confirm the infection and to analyze the TNFα gene polymorphisms.RESULTS:
Cryptococcus neoformans was detected as the predominant etiological agent (100%) in HIV-positive patients. No genetic polymorphic changes were found.CONCLUSIONS:
No correlation was observed between the analyzed TNFα polymorphisms and cryptococcal meningitis.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Factor de Necrosis Tumoral alfa
/
Meningitis Criptocócica
Tipo de estudio:
Estudio de prevalencia
/
Factores de riesgo
Límite:
Adolescente
/
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal do Pará/BR
/
Universidade do Estado do Pará/BR
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