Modeling of lactose enzymatic hydrolysis using Monte Carlo method
Electron. j. biotechnol
;
40: 78-83, July. 2019. tab, graf, ilus
Artículo
en Inglés
| LILACS
| ID: biblio-1053493
ABSTRACT
Background:
Mathematical modeling is useful in the analysis, prediction, and optimization of an enzymatic process. Unlike the conventional modeling methods, Monte Carlo method has special advantages in providing representations of the molecule's spatial distribution. However, thus far, Monte Carlo modeling of enzymatic system is namely based on unimolecular basis, not suitable for practical applications. In this research, Monte Carlo modeling is performed for enzymatic hydrolysis of lactose for the purpose of real-time applications.Results:
The enzyme hydrolysis of lactose, which is conformed to MichaelisMenten kinetics, is modeled using the Monte Carlo modeling method, and the simulation results prove that the model predicts the reaction kinetics very well.Conclusions:
Monte Carlo modeling method can be used to model enzymatic reactions in a simple way for real-time applications.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Método de Montecarlo
/
Enzimas
/
Hidrólisis
/
Lactosa
Tipo de estudio:
Evaluación Económica en Salud
/
Estudio pronóstico
Idioma:
Inglés
Revista:
Electron. j. biotechnol
Asunto de la revista:
Biotecnologia
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
China
Institución/País de afiliación:
Shandong Academy of Chinese Medicine/CN
/
Shandong Academy of Pharmaceutical Sciences/CN
/
Shandong Normal University/CN
/
Shandong University/CN
/
Shandong Yian Biotechnology Co/CN
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