Investigation of carbapenemases and aminoglycoside modifying enzymes of Acinetobacter baumannii isolates recovered from patients admitted to intensive care units in a tertiary-care hospital in Brazil
Rev. Soc. Bras. Med. Trop
;
53: e20190044, 2020. tab
Artículo
en Inglés
| LILACS
| ID: biblio-1057279
ABSTRACT
Abstract INTRODUCTION: Acinetobacter baumannii are opportunistic bacteria, highly capable of acquiring antimicrobial resistance through the production of carbapenemases and aminoglycoside modifying enzymes (AMEs). METHODS: Carbapenemase and AME genes were investigated in A. baumannii recovered from inpatients of a Brazilian hospital. RESULTS: The key genes found were bla OXA-51-like, the association ISAba1- bla OXA-23-like, and the AME genes aph(3´)-VI, aac(6´)-Ib, aac(3)-Ia, and aph(3´)-Ia. Different clusters spread through the institution wards. CONCLUSIONS: The dissemination of bla OXA-23-like and AME-carrying A. baumannii through the hospital highlights the need for improved preventive measures to reduce the spread of infection.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Proteínas Bacterianas
/
Beta-Lactamasas
/
Infecciones por Acinetobacter
/
Acinetobacter baumannii
/
Aminoglicósidos
Límite:
Humanos
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Faculdade de Medicina de São José do Rio Preto/BR
/
Instituto Adolfo Lutz/BR
/
Universidade Federal de São Carlos/BR
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