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Composition of the bacterial community in the gastrointestinal tract of Kunming mice
Han, Xufeng; Shao, Haiyan; Wang, Yi; Hu, Ankang; Chen, Renjin; Chen, Quangang.
  • Han, Xufeng; Xuzhou Medical University. Laboratory Animal Center. Xuzhou. CN
  • Shao, Haiyan; Xuzhou Oriental People's Hospital. Psychological Counseling and Treatment Center. Xuzhou. CN
  • Wang, Yi; Xuzhou Medical University. Laboratory Animal Center. Xuzhou. CN
  • Hu, Ankang; Xuzhou Medical University. Laboratory Animal Center. Xuzhou. CN
  • Chen, Renjin; Xuzhou Medical University. Laboratory Animal Center. Xuzhou. CN
  • Chen, Quangang; Xuzhou Medical University. Laboratory Animal Center. Xuzhou. CN
Electron. j. biotechnol ; 43: 16-22, Jan. 2020. tab, graf
Artículo en Inglés | LILACS | ID: biblio-1087512
ABSTRACT

Background:

The intestinal bacterial community has an important role in maintaining human health. Dysbiosis is a key inducer of many chronic diseases including obesity and diabetes. Kunming mice are frequently used as a model of human disease and yet little is known about the bacterial microbiome resident to the gastrointestinal tract.

Results:

We undertook metagenomic sequencing of the luminal contents of the stomach, duodenum, jejunum, ileum, cecum, colon, and rectum of Kunming mice. Firmicutes was the dominant bacterial phylum of each intestinal tract and Lactobacillus the dominant genus. However, the bacterial composition differed among the seven intestinal tracts of Kunming mice. Compared with the small intestine, the large intestine bacterial community of Kunming mice is more stable and diverse.

Conclusions:

To our knowledge, ours is the first study to systematically describe the gastrointestinal bacterial composition of Kunming mice. Our findings provide a better understanding of the bacterial composition of Kunming mice and serves as a foundation for the study of precision medicine.
Asunto(s)


Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Bacterias / Tracto Gastrointestinal Tipo de estudio: Estudio pronóstico Límite: Animales Idioma: Inglés Revista: Electron. j. biotechnol Asunto de la revista: Biotecnologia Año: 2020 Tipo del documento: Artículo País de afiliación: China Institución/País de afiliación: Xuzhou Medical University/CN / Xuzhou Oriental People's Hospital/CN

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Bacterias / Tracto Gastrointestinal Tipo de estudio: Estudio pronóstico Límite: Animales Idioma: Inglés Revista: Electron. j. biotechnol Asunto de la revista: Biotecnologia Año: 2020 Tipo del documento: Artículo País de afiliación: China Institución/País de afiliación: Xuzhou Medical University/CN / Xuzhou Oriental People's Hospital/CN