Recommendations from the Brazilian society of rheumatology for the diagnosis of Sjögren's syndrome (Part I): glandular manifestations (systematic review)
Adv Rheumatol
;
59: 58, 2019. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1088581
ABSTRACT
Abstract Background:
Primary Sjögren's syndrome (pSS) is a systemic immune-mediated disease whose main characteristic is exocrine gland inflammation and, subsequent reduction in tear and saliva production. A delayed diagnosis is common due to the nonspecific clinical manifestations of disease. The aim of the present study was to develop recommendations for the diagnosis of glandular manifestations of pSS based on evidence and expert opinion. Main body of the abstract We conducted a systematic literature review to retrieve the best evidence available on the accuracy of diagnostic tests for pSS. We also held two in-person meetings with experts (rheumatologists, pathologists, ophthalmologists and dentists) to establish their level of agreement using the Delphi method. Ultimately, we generated 18 recommendations that aim to facilitate the diagnosis of the glandular manifestations of pSS.Conclusion:
The diagnosis of glandular manifestations of pSS is complex and multidisciplinary. It requires specific knowledge in the field of ophthalmology, immunology, pathology and imaging, making it compulsory for the rheumatologist to work with professionals from these different areas in order to improve accuracy and early diagnosis. Glandular dysfunction tests, ANA, RF, Anti-Ro, protein electrophoresis, urinalysis, blood count, C-Reactive protein, complement, testing for syphilis and viruses (HCV, HIV) and SGUS should be investigated when dryness or systemic manifestation are present. Minor salivary gland biopsy is recommended for all anti-Ro negative or incomplete criteria cases.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Síndrome de Sjögren
Tipo de estudio:
Estudio diagnóstico
/
Guía de Práctica Clínica
/
Estudio de tamizaje
/
Revisiones Sistemáticas Evaluadas
Límite:
Humanos
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Adv Rheumatol
Asunto de la revista:
Artrite
/
Reumatologia
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Hospital Federal dos Semidores do Estado do Rio de Janeiro/BR
/
Hospital das Clínicas da Faculdade de Medicina da USP/BR
/
Santa Casa de Sao Paulo/BR
/
UNICAMP/BR
/
Universidade Federal de Ciencias da Saúde de Porto Alegre/BR
/
Universidade Federal de Minas Gerais/BR
/
Universidade Federal de Paraíba/BR
/
Universidade Federal de Pernambuco/BR
/
Universidade Federal de Santa Catarina/BR
/
Universidade Federal de Sao Paulo/BR
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