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Cutaneous sarcoidosis: clinico-epidemiological profile of 72 patients at a tertiary hospital in São Paulo, Brazil,
Hospital das ClínicasTorquato, Mariana Fernandes; Hospital das ClínicasCosta, Marcella Karen Souza da; Hospital das ClínicasNico, Marcello Menta Simonsen.
  • Hospital das ClínicasTorquato, Mariana Fernandes; Universidade de São Paulo. Faculdade de Medicina. Hospital das ClínicasTorquato, Mariana Fernandes. São Paulo. BR
  • Hospital das ClínicasCosta, Marcella Karen Souza da; Universidade de São Paulo. Faculdade de Medicina. Hospital das ClínicasCosta, Marcella Karen Souza da. São Paulo. BR
  • Hospital das ClínicasNico, Marcello Menta Simonsen; Universidade de São Paulo. Faculdade de Medicina. Hospital das ClínicasNico, Marcello Menta Simonsen. São Paulo. BR
An. bras. dermatol ; 95(1): 57-62, Jan.-Feb. 2020. tab, graf
Artículo en Inglés | LILACS | ID: biblio-1088735
ABSTRACT
Abstract Background: Sarcoidosis is a multisystem disease of unknown cause that is characterized by the presence of granulomas in various organs. Cutaneous involvement is common and the reported incidence has varied from 9% to 37%. Studies on cutaneous sarcoidosis in Brazil are lacking. Objectives: To describe the clinical and epidemiological aspects of patients with cutaneous sarcoidosis diagnosed at the Department of Dermatology of the University of São Paulo, from May 1994 to March 2018. Methods: Clinical data of patients with confirmed cutaneous sarcoidosis were retrospectively reviewed and classified according to gender, ethnicity, age at diagnosis, cutaneous presentation, systemic involvement and treatment. Results: Cutaneous sarcoidosis was diagnosed in 72 patients with a female predominance (74%). The mean age at diagnosis was 49.6 years and most of the patients were white (61%). Papules and plaques were the most common lesions. Systemic sarcoidosis was detected in 81% of patients, affecting mainly the lungs and thoracic lymph nodes (97%). Typically, cutaneous lesions were the first manifestation (74%). Systemic therapy was necessary for 72% of patients; the dermatologist managed many of these cases. Oral glucocorticoids were the most commonly used systemic medication (92%). The mean number of systemic drugs used was 1.98 per patient. Limitations: Insufficient data in medical records. Conclusions: This series highlights the dermatologist role in recognizing and diagnosing cutaneous sarcoidosis, evaluating patients for systemic disease involvement and treating the skin manifestations. Cutaneous sarcoidosis was once considered exceedingly infrequent in Brazil in comparison to infectious granulomatous diseases; however, the present series seems to suggest that the disease is not so rare in this region.
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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Sarcoidosis / Enfermedades de la Piel / Centros de Atención Terciaria Tipo de estudio: Estudio de incidencia / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Adulto / Anciano / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: An. bras. dermatol Asunto de la revista: Dermatologia Año: 2020 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Universidade de São Paulo/BR

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Sarcoidosis / Enfermedades de la Piel / Centros de Atención Terciaria Tipo de estudio: Estudio de incidencia / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Adulto / Anciano / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: An. bras. dermatol Asunto de la revista: Dermatologia Año: 2020 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Universidade de São Paulo/BR