Hyptis brevipes and Paullinia pinnata extracts and their fractions presenting activity against Mycobacterium abscessos SubSP. massiliense
Rev. patol. trop
;
48(3): 148-160, 2019.
Artículo
en Inglés
| LILACS
| ID: biblio-1096710
ABSTRACT
Medicinal plants are of great interest for the discovery of new biomolecules with diversified effects. Over the last decade different outbreaks caused by Mycobacterium abscessos subsp. Massiliense have been reported, evidencing it as an important emerging pathogen in underdeveloped countries. This study investigated the antimycobacterial activity of six Brazilian medicinal plant extracts and their fractions. Hyptis brevipes, Tocoyena formosa, Randia armata, Paullinia pinnata, La foensia pacari And Anadenanthera colubrina were evaluated against M. a. massiliense. Total extracts from the medicinal plants H. brevipes, T. formosa, P. pinnata and L. pacari presented a minimal bactericidal concentration of 1 mg/mL. After fractioning, the ethanolic fractions from H. brevipes and P. pinnata presented bactericidal activity, and the ethyl acetate fraction from H. brevipes and T. formosa presented antimycobacterial action. The best bactericidal function of all plant fractions was the ethanolic, which contained rutin and rosmarinic acid that were shown to have microbicidal activity.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Plantas Medicinales
/
Hyptis
/
Paullinia
/
Biodiversidad
/
Mycobacterium abscessus
Idioma:
Inglés
Revista:
Rev. patol. trop
Asunto de la revista:
Medicina Tropical
/
Patología
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal de Goiás/BR
/
Universidade Federal do Mato Grosso do Sul/BR
/
Universidade Fedral do Mato Grosso do Sul/BR
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