Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study
São Paulo med. j
; 138(1): 19-26, Jan.-Feb. 2020. tab, graf
Article
en En
| LILACS
| ID: biblio-1099388
Biblioteca responsable:
BR1.1
ABSTRACT
ABSTRACT BACKGROUND:
Studies have shown that physical activity levels can be inversely associated with high-sensitivity C-reactive protein (hs-CRP) levels. However, the amount of physical activity required to maintain normal hs-CRP levels is still a matter for speculation.OBJECTIVE:
To identify the amount of physical activity necessary to discriminate the hs-CRP levels in adults. DESIGN ANDSETTING:
Cross-sectional study at six teaching and research institutions.METHODS:
The study sample comprised 10,231 adults aged 35 to 74 years who were participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Receiver operating characteristic (ROC) curves were constructed to compare the amount of physical activity in two domains (leisure time and commuting) with hs-CRP levels. The sensitivity and specificity were calculated to identify the best cutoff for physical activity level that would be needed to maintain normal levels of hs-CRP (< 3 mg/l).RESULTS:
The area under the ROC curve was only statistically significant for discriminating normal levels of hs-CRP according to the amount of physical activity when the two study domains were added together. The accumulated physical activity level of 200 minutes/week was the best cutoff for discriminating normal levels of hs-CRP in adults of both sex.CONCLUSIONS:
Physical activity in the leisure-time and commuting domains together, of duration 200 minutes/week, was associated with normal hs-CRP values.Palabras clave
Texto completo:
1
Índice:
LILACS
Asunto principal:
Proteína C-Reactiva
/
Ejercicio Físico
Tipo de estudio:
Diagnostic_studies
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Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adult
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Aged
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Humans
País/Región como asunto:
America do sul
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Brasil
Idioma:
En
Revista:
São Paulo med. j
Asunto de la revista:
Cirurgia Geral
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Cincia
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Ginecologia
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MEDICINA
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Medicina Interna
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Obstetr¡cia
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Pediatria
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Sa£de Mental
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Sa£de P£blica
Año:
2020
Tipo del documento:
Article