Dental Pulpal Tissue Regeneration, Pulpal Vitality Testing, and Healing of Apical Lesions Following Stem Cell Transplant: A Systematic Review and Meta-Analysis
Pesqui. bras. odontopediatria clín. integr
;
20: e5383, 2020. tab, graf
Artículo
en Inglés
| LILACS, BBO
| ID: biblio-1101293
ABSTRACT
Abstract Objective:
To analyze data obtained from animal and human studies using stem cells. Material andMethods:
Medical Literature Analysis and Retrieval System Online (MEDLINE), PubMed, Cochrane Library, Embase, Information Sciences Institute (ISI), as well as Google Scholar were utilized and searched as available electronic databases to perform a systematic literature review of articles published between 2010 and 2019. The Endnote X9 for Windows was also employed to manage electronic titles and abstracts of the selected studies. Searches were conducted using keywords of "pulpal OR pulpal tissue OR pulpal vitality", "regeneration", "apical healing", "stem cells OR progenitor cells", and "mediated pulpal tissue". Consequently, 189 titles and abstracts endowed with potential relevance were discovered based on searches into manual and electronic sources. Ultimately, a total of six articles met the inclusion criteria in the present systematic review and meta-analysis.Results:
Out of the six articles identified and selected, five studies were categorized as animal experiments and one article was nominated as a human clinical trial. The greatest bias risks were accordingly observed in the majority of animal examinations, but articles related to humans revealed decreased risks of bias, while the human clinical trial showed some concerns.Conclusion:
Promising parameters testing functional pulp regeneration could be represented through stem cell transplants.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Células Madre
/
Regeneración Ósea
/
Pulpa Dental
/
Endodoncia
/
Revisiones Sistemáticas como Asunto
Tipo de estudio:
Guía de Práctica Clínica
/
Estudio pronóstico
/
Revisiones Sistemáticas Evaluadas
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Pesqui. bras. odontopediatria clín. integr
Asunto de la revista:
Odontología
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
China
/
Irán
Institución/País de afiliación:
Guilan University of Medical Sciences/IR
/
Kerman University of Medical Sciences/IR
/
Shahid Beheshti University of Medical Sciences/IR
/
Tehran University of Medical Sciences/IR
/
Urmia University of Medical Sciences/IR
/
Xi'an Jiaotong University/CN
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