Early diagnosis and treatment of Alzheimers disease: new definitions and challenges
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
42(4): 431-441, July-Aug. 2020. tab
Artículo
en Inglés
| LILACS
| ID: biblio-1132093
ABSTRACT
The prevalence of Alzheimer's disease (AD), a progressive neurodegenerative disorder, is expected to more than double by 2050. Studies on the pathophysiology of AD have been changing our understanding of this disorder and setting a new scenario for drug development and other therapies. Concepts like the "amyloid cascade" and the "continuum of AD," discussed in this article, are now well established. From updated classifications and recommendations to advances in biomarkers of AD, we aim to critically assess the literature on AD, addressing new definitions and challenges that emerged from recent studies on the subject. Updates on the status of major clinical trials are also given, and future perspectives are discussed.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Encéfalo
/
Diagnóstico Precoz
/
Enfermedad de Alzheimer
Tipo de estudio:
Estudio diagnóstico
/
Guía de Práctica Clínica
/
Factores de riesgo
/
Estudio de tamizaje
Límite:
Humanos
Idioma:
Inglés
Revista:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Asunto de la revista:
Psiquiatria
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Departamento e Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HCFMUSP)/BR
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