Heart failure with preserved ejection fraction: an update on pathophysiology, diagnosis, treatment, and prognosis
Braz. j. med. biol. res
;
53(7): e9646, 2020. graf
Artículo
en Inglés
| LILACS, ColecionaSUS
| ID: biblio-1132528
ABSTRACT
Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical syndrome in which patients have symptoms and signs of HF with normal or near-normal left ventricular ejection fraction (LVEF ≥50%). Roughly half of all patients with HF worldwide have an LVEF ≥50% and nearly half have an LVEF <50%. Thanks to the increased scientific attention about the condition and improved characterization and diagnostic tools, the incidence of HF with reduced ejection fraction (HFrEF) dropped while that of HFpEF has increased by 45%. HFpEF has no single guideline for diagnosis or treatment, the patient population is heterogeneously and inconsistently described, and longitudinal studies are lacking. To better understand and overcome the disease, in this review, we updated the latest knowledge of HFpEF pathophysiology, introduced the existing promising diagnostic methods and treatments, and summarized its prognosis by reviewing the most recent cohort studies.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Volumen Sistólico
/
Función Ventricular Izquierda
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Insuficiencia Cardíaca
Tipo de estudio:
Estudio diagnóstico
/
Guía de Práctica Clínica
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Humanos
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Año:
2020
Tipo del documento:
Artículo
Institución/País de afiliación:
Berlin Institute of Health Center for Regenerative Therapies & Berlin - Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum (CVK)/DE
/
Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health/DE
/
Henan Provincial Peoples Hospital/CN
/
Second Affiliated Hospital of Zhengzhou University/CN
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