Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats
J. appl. oral sci
;
28: e20190384, 2020. tab, graf
Artículo
en Inglés
| LILACS, BBO
| ID: biblio-1134801
ABSTRACT
Abstract Objectives This study evaluated if the use of a bioactive glass-ceramic-based gel, named Biosilicate (BS), before, after or mixed with bleaching gel, could influence the inflammation of the dental pulp tissue of rats' molars undergoing dental bleaching with hydrogen peroxide (H2O2). Methodology The upper molars of Wistar rats (Rattus norvegicus, albinus) were divided into Ble bleached (35% H2O2, 30-min); Ble-BS bleached and followed by BS-based gel application (20 min); BS-Ble BS-based gel application and then bleaching; BS/7d-Ble BS-based gel applications for 7 days and then bleaching; Ble+BS blend of H2O2 with BS-based gel (11, 30-min); and control placebo gel. After 2 and 30 days (n=10), the rats were euthanized for histological evaluation. The Kruskal-Wallis and Dunn statistical tests were performed (P<0.05). Results At 2 days, the Ble and Ble-BS groups had significant alterations in the pulp tissue, with an area of necrosis. The groups with the application of BS-based gel before H2O2 had moderate inflammation and partial disorganization in the occlusal third of the coronary pulp and were significantly different from the Ble in the middle and cervical thirds (P<0.05). The most favorable results were observed in the Ble+BS, which was similar to the control in all thirds of the coronary pulp (P>0.05). At 30 days, the pulp tissue was organized and the bleached groups presented tertiary dentin deposition. The Ble group had the highest deposition of tertiary dentin, followed by the Ble-BS, and both were different from control (P<0.05). Conclusion A single BS-based gel application beforehand or BS-based gel blended with a bleaching gel minimize the pulp damage induced by dental bleaching.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Pulpitis
/
Blanqueamiento de Dientes
/
Pulpa Dental
/
Blanqueadores Dentales
/
Vidrio
/
Peróxido de Hidrógeno
Tipo de estudio:
Estudios de evaluación
Límite:
Animales
Idioma:
Inglés
Revista:
J. appl. oral sci
Asunto de la revista:
Odontología
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Estadual Paulista/BR
/
Universidade Federal de São Carlos/BR
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