Superinfection exclusion studies using West Nile virus and Culex flavivirus strains from Argentina
Mem. Inst. Oswaldo Cruz
;
115: e200012, 2020. tab, graf
Artículo
en Inglés
| LILACS, SES-SP
| ID: biblio-1135267
ABSTRACT
In Argentina, many Flavivirus were recognised including West Nile virus (WNV). During 2009 several strains of Culex Flavivirus (CxFV), an insect-specific flavivirus, were isolated in the same region where circulation of WNV was detected. Hence, the objective of this study was to analyse the effect of co-infection in vitro assays using CxFV and WNV Argentinean strains in order to evaluate if CxFV could affect WNV replication. Our results showed that WNV replication was suppressed when multiplicity of infection (MOI) for CxFV was 10 or 100 times higher than WNV. Nevertheless, in vivo assays are necessary in order to evaluate the superinfection exclusion potential.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Virus del Nilo Occidental
/
Sobreinfección
/
Culex
/
Flavivirus
/
Insectos Vectores
Límite:
Animales
País/Región como asunto:
America del Sur
/
Argentina
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Año:
2020
Tipo del documento:
Artículo
Institución/País de afiliación:
Instituto Nacional de Enfermedades Virales Humanas Dr Julio I Maiztegui/AR
/
Århus University/DK
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