Protein Profiles of Individuals with Erosive Tooth Wear
Pesqui. bras. odontopediatria clín. integr
;
20: e0026, 2020. tab
Artículo
en Inglés
| LILACS, BBO
| ID: biblio-1135483
ABSTRACT
Abstract Objective:
To determine if protein profiles identified in saliva could be used to determine risk and severity of erosive tooth wear. Material andMethods:
Three types of saliva sampling were performed to obtain saliva from 34 18-year old individuals that received regular dental check-ups, along with clinical status of the dentition and risk factor related to erosive tooth wear using the VEDE scale. Protein profiles in saliva were determined using electrophoresis and the calculation of the percentage of a specific band at a specific molecular weight in relationship to the total protein in that sample (% of total) using molecular weight standards. This quantification was repeated for each protein band across a range of molecular weights for each sample to test for association with erosive tooth wear status.Results:
There were no differences in the number of detectable proteins sourced from the parotid gland, nor the unstimulated and stimulated whole saliva. Five out of the 34 individuals had no signs of erosive tooth wear despite an acidic diet and were more likely to have proteins with molecular weight smaller than 1 KDa (p=0.03).Conclusion:
There is potential for the use of protein profiling to determine risks for erosive tooth wear.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Erosión de los Dientes
/
Factores de Riesgo
/
Caries Dental
/
Esmalte Dental
/
Desgaste de los Dientes
Tipo de estudio:
Estudio de etiología
/
Guía de Práctica Clínica
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adolescente
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
Europa
Idioma:
Inglés
Revista:
Pesqui. bras. odontopediatria clín. integr
Asunto de la revista:
Odontología
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Estados Unidos
Institución/País de afiliación:
University of Arizona/US
/
University of Pittsburgh/US
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