Interaction of Biomphalaria cells in primary cultures with Schistosoma mansoni sporocysts
Rev. Soc. Bras. Med. Trop
;
53: e20200257, 2020. graf
Artículo
en Inglés
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136878
ABSTRACT
Abstract INTRODUCTION:
Biomphalaria snails may display varying levels of susceptibility to Schistosoma mansoni infection. We have been developing an in vitro model to study the interaction between the snail and the parasite, using tissue-derived cell cultures from Biomphalaria.METHODS:
The digestive gland- and kidney-derived cells from primary cultures of resistant (B. tenagophila Taim) and susceptible (B. tenagophila HM and B. glabrata BH) strains of Biomphalaria were exposed to S. mansoni sporocysts.RESULTS:
S. mansoni sporocysts were surrounded and encapsulated exclusively by cells derived from the digestive gland (DG) of B. tenagophila Taim. The process was followed by a marked decrease in the number of free sporocysts in the culture medium. The morphological characteristics of DG-derived cells in culture have been described.CONCLUSIONS:
Cells derived from DG (but not SK) primary cultures of B. tenagophila Taim may participate in S. mansoni sporocyst control.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Biomphalaria
/
Esquistosomiasis mansoni
Tipo de estudio:
Estudio pronóstico
Límite:
Animales
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Año:
2020
Tipo del documento:
Artículo
Institución/País de afiliación:
Fundação Ezequiel Dias/BR
/
Fundação Oswaldo Cruz/BR
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