Transmission and prevalence of drug-resistant tuberculosis in a Brazilian setting under a directly observed therapy short-course strategy
Rev. Soc. Bras. Med. Trop
;
53: e20190404, 2020. tab, graf
Artículo
en Inglés
| SES-SP, ColecionaSUS, LILACS
| ID: biblio-1136910
ABSTRACT
Abstract INTRODUCTION:
We aimed to estimate the prevalence and transmission of drug-resistant tuberculosis in a high-burden Brazilian setting under directly observed therapy short-course strategy.METHODS:
Isolates of culture-confirmed pulmonary tuberculosis patients from Guarulhos, Brazil, diagnosed in October 2007-2011 were subjected to drug susceptibility and IS6110-restriction fragment length polymorphism testing.RESULTS:
The overall resistance prevalence was 11.5% and the multi-drug resistance rate was 4.2%. Twenty-six (43.3%) of 60 drug-resistant isolates were clustered. Epidemiological relationships were identified in 11 (42.3%) patients; 30.8% of the cases were transmitted in households.CONCLUSIONS:
Drug-resistant tuberculosis was relatively low and transmitted in households and the community.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Polimorfismo de Longitud del Fragmento de Restricción
/
Brasil
/
Prevalencia
/
Estudios Transversales
/
Tuberculosis Resistente a Múltiples Medicamentos
/
Terapia por Observación Directa
/
Mycobacterium tuberculosis
Tipo de estudio:
Estudio observacional
/
Estudio de prevalencia
/
Factores de riesgo
Límite:
Adolescente
/
Adulto
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Año:
2020
Tipo del documento:
Artículo
Institución/País de afiliación:
Instituto Adolfo Lutz/BR
/
Secretaria de Saúde do Estado de São Paulo/BR
/
Universidade de São Paulo/BR
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