Associations between serum calcium, 25(OH)D level and bone mineral density in adolescents
Adv Rheumatol
;
61: 16, 2021. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1152746
ABSTRACT
Abstract Backgrounds It is important to improve our understanding of the roles of calcium and vitamin D in bone health for preventing osteoporosis. We aimed at exploring the associations between serum calcium, vitamin D level, and bone mineral density (BMD) in adolescents included in the National Health and Nutrition Examination Survey (NHANES) 2001 - 2006. Methods:
Weighted multivariate linear regression models were used to estimate the associations of serum calcium, 25(OH)D level with total BMD. Smooth curve fitting was used to explore the potential non-linear relationship.Results:
A total of 5990 individuals aged between 12 and 19 years were included in this study. The fully-adjusted model showed serum calcium positively correlated with total BMD. However, an inverted U-shaped relationship was found when we performed the smooth curve fitting method, and the inflection point was calculated at 9.6 mg/dL using the two-piecewise linear regression model. In contrast, there was a positive correlation between serum 25(OH)D and total BMD after adjusting for potential confounders.Conclusions:
The present study revealed a positive correlation between serum 25(OH)D level and total BMD, and an inverted U-shaped relationship between serum calcium and total BMD.(AU)
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Vitamina D
/
Densidad Ósea
/
Calcio
Tipo de estudio:
Estudio pronóstico
/
Factores de riesgo
Límite:
Adolescente
/
Humanos
Idioma:
Inglés
Revista:
Adv Rheumatol
Asunto de la revista:
Artrite
/
Reumatologia
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
China
Institución/País de afiliación:
Xiaoshan Affiliated Hospital of Wenzhou Medical University/CN
/
Zhejiang Xiaoshan Hospital/CN
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