Effects of Curcumin on Sodium Arsenite Induced Neoplastic Cell Transformation in Balb/c 3T3 Cells

Demircioglu, Busra; Aydin, Yasemin; Orta-Yilmaz, Banu; Yildizbayrak, Nebahat; Erkan, Melike

Demircioglu, Busra; Aydin, Yasemin; Orta-Yilmaz, Banu; Yildizbayrak, Nebahat; Erkan, Melike.

Demircioglu, Busra; Istanbul University. Institute of Graduate Studies in Sciences. Department of Biology. Istanbul. TR
Aydin, Yasemin; Istanbul University. Faculty of Science. Department of Biology. Istanbul. TR
Orta-Yilmaz, Banu; Istanbul University. Faculty of Science. Department of Biology. Istanbul. TR
Yildizbayrak, Nebahat; Istanbul University. Faculty of Science. Department of Biology. Istanbul. TR
Erkan, Melike; Istanbul University. Faculty of Science. Department of Biology. Istanbul. TR

Braz. arch. biol. technol ; 64: e21200093, 2021. tab, graf

Artículo en Inglés | LILACS | ID: biblio-1153294

ABSTRACT

ABSTRACT

HIGHLIGHTS Sodium arsenite can cause neoplastic transformation in cells. Curcumin reduced cell viability and increased LDH activity in transformed Balb/c 3T3 cells. Curcumin caused DNA damage in transformed Balb/c 3T3 cells. Curcumin may play a protective role in sodium arsenite-induced toxicity.

Asunto(s)

Animales; Ratones; Arsénico/toxicidad; Daño del ADN; Transformación Celular Neoplásica; Curcumina/farmacología; Fibroblastos/efectos de los fármacos; Células 3T3 BALB; Fibroblastos/patología

Cancer; Curcumin; Embryonic fibroblast cells; Genotoxicity; Sodium arsenite

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Arsénico / Daño del ADN / Transformación Celular Neoplásica / Curcumina / Fibroblastos Límite: Animales Idioma: Inglés Revista: Braz. arch. biol. technol Asunto de la revista: Biologia Año: 2021 Tipo del documento: Artículo País de afiliación: Turquía Institución/País de afiliación: Istanbul University/TR

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