The C677T thermolabile variant of methylene tetrahydrofolate reductase on homocysteine, folate and vitamin B12 in a hemodialysis center
Medicina (B.Aires)
;
62(2): 149-153, 2002.
Artículo
en Español
| LILACS, BINACIS
| ID: biblio-1165113
ABSTRACT
Homocysteine is a risk factor for cardiovascular disease. Mutations in a key enzyme in homocysteine metabolism, methylenetetrahydrofolate reductase, may contribute to hyperhomocysteinemia and alter folate and cobalamin levels. After starting hemodialysis, 10 mg oral folate daily and 500 micrograms intravenous methylcobalamin once weekly were prescribed to 27 hemodialysis patients (time on hemodialysis > or = 12 months) and two groups were defined Group A normal; Group B heterozygous. Initial, third and twelfth month measurements of homocysteine, serum folate and vitamin B12 levels were collected and analyzed. Heterozygous state of methylenetetrahydrofolate reductase prevalence was 48
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Índice:
LILACS (Américas)
Asunto principal:
Vitamina B 12
/
Ácido Fólico
/
Oxidorreductasas actuantes sobre Donantes de Grupo CH-NH
/
Homocisteína
/
Fallo Renal Crónico
Tipo de estudio:
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Español
Revista:
Medicina (B.Aires)
Asunto de la revista:
Medicina
Año:
2002
Tipo del documento:
Artículo
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