Gangliocytic paraganglioma of the spine
Autops. Case Rep
;
11: e2021277, 2021. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1249021
ABSTRACT
Paragangliomas are rare, encapsulated, benign neuroendocrine tumors that can arise from the adrenal medulla or extra-adrenal paraganglia. Extra-adrenal paragangliomas may develop a gangliocytic component with ganglion cells (Gangliocytic paragangliomas). Nearly 25%of cauda equina paragangliomas are gangliocytic paragangliomas. Here, we describe the case of a 35-year-old male who presented with weakness of both lower limbs over the last two months. Radiological findings were suggestive of myxopapillary ependymoma. However, the histopathological examination revealed a tumor with cells arranged in sheets, papillae, lobules, and around vessels forming pseudo rosettes. Ganglion cells were seen in small groups and, also singly. Tumor cells were immunopositive for chromogranin, synaptophysin, and S-100. Ganglion cells were immunopositive for synaptophysin, NSE, and NFP. A final histological diagnosis of Gangliocytic paraganglioma (WHO grade I) was made. To date, only nine gangliocytic paraganglioma cases have been previously reported, and to the best of our knowledge, this is the largest gangliocytic paraganglioma.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Paraganglioma
/
Neoplasias de la Columna Vertebral
Límite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Autops. Case Rep
Asunto de la revista:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
India
Institución/País de afiliación:
Guru Teg Bahadur Hospital/IN
/
Institute of Human Behaviour and Allied Sciences/IN
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