Laboratory diagnosis of human T-lymphotropic virus in Brazil: assays, flowcharts, challenges, and perspectives
Rev. Soc. Bras. Med. Trop
;
54: e01752021, 2021. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1250822
ABSTRACT
Abstract INTRODUCTION We present a data analysis and review of recent studies regarding the laboratory diagnosis of human T-lymphotropic virus 1 and 2 (HTLV-1/2) infections in Brazil. METHODS Target populations, available diagnostic serological assays (screening and complementary tests), molecular assays (in-house), causes of false-positive and false-negative results, and flowcharts were analyzed. RESULTS A table presents the target populations, two diagnostic flowcharts (depending on laboratory infrastructure and study population), and recent research that may improve how HTLV-1/2 is diagnosed in Brazil. CONCLUSIONS: Our results support the implementation of public policies to reduce HTLV-1/2 transmission and its associated diseases.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Virus Linfotrópico T Tipo 1 Humano
/
Infecciones por HTLV-I
/
Infecciones por HTLV-II
/
Técnicas de Laboratorio Clínico
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
Brasil
/
Reino Unido
Institución/País de afiliación:
Escola Bahiana de Medicina e Saúde Pública/BR
/
Imperial College Healthcare NHS Trust/GB
/
Instituto Adolfo Lutz/BR
/
Ministério da Saúde/BR
/
Universidade Federal de Minas Gerais/BR
/
Universidade Federal do Espírito Santo/BR
/
Universidade Federal do Pará/BR
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