Transcriptome profiling reveals differential expression of genes potentially involved in muscle and adipose tissue development of cattle
Electron. j. biotechnol
;
48: 72-77, nov. 2020. tab, ilus
Artículo
en Inglés
| LILACS
| ID: biblio-1254810
ABSTRACT
BACKGROUND:
To identify differentially expressed genes (DEGs) between muscle and adipose in cattle, we analyzed the data from the RNA sequencing of three Angus×Qinchuan crossbred cattle.RESULTS:
Searched the Gene Expression Omnibus (GEO) for a microarray dataset of Yan yellow cattle, GSE49992. After the DEGs were identified, we used STRING and Cytoscape to construct a proteinprotein interaction (PPI) network, subsequently analyzing the major modules of key genes. In total, 340 DEGs were discovered, including 21 hub genes, which were mainly enriched in muscle contraction, skeletal muscle contraction, troponin complex, lipid particle, Z disc, tropomyosin binding, and actin filament binding.CONCLUSIONS:
In summary, these genes can be regarded as candidate biomarkers for the regulation of muscle and adipose development.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Tejido Adiposo
/
Desarrollo de Músculos
/
Transcriptoma
Límite:
Animales
Idioma:
Inglés
Revista:
Electron. j. biotechnol
Asunto de la revista:
Biotecnologia
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
China
/
Nueva Zelanda
/
Estados Unidos
Institución/País de afiliación:
Massey University/NZ
/
Northwest A&F University/CN
/
Utah State University/US
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