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Admission hyperglycemia and associated risk factors among patients with acute stroke in intensive care units in Kinshasa, the Democratic Republic of the Congo
Tshituta, Josée Nkongolo; Lepira, Francois Bompeka; Kajingulu, François Musungay; Rissassy Makulo, Jean Robert; Kiswaya Sumaili, Ernest; Zalagali Akilimali, Pierre; Natuhoyila Nkodila, Aliocha; Mbuyi wa Mukishi, Freddy; Masewu, Angèle I; Ngondo Mutombo, Stéphane; Bibonge Amisi, Eric; Mwena Ilunga, Jean Pierre; Dibue Mbombo, Wilfrid; Miteo Mukuna, Patrick; Manzaza Kilembe, Adolphe.
  • Tshituta, Josée Nkongolo; s.af
  • Lepira, Francois Bompeka; s.af
  • Kajingulu, François Musungay; s.af
  • Rissassy Makulo, Jean Robert; s.af
  • Kiswaya Sumaili, Ernest; s.af
  • Zalagali Akilimali, Pierre; s.af
  • Natuhoyila Nkodila, Aliocha; s.af
  • Mbuyi wa Mukishi, Freddy; s.af
  • Masewu, Angèle I; s.af
  • Ngondo Mutombo, Stéphane; s.af
  • Bibonge Amisi, Eric; s.af
  • Mwena Ilunga, Jean Pierre; s.af
  • Dibue Mbombo, Wilfrid; s.af
  • Miteo Mukuna, Patrick; s.af
  • Manzaza Kilembe, Adolphe; s.af
Ann. afr. méd. (En ligne) ; 13(4): 3783-3794, 2020. tab
Artículo en Inglés | AIM | ID: biblio-1259093
ABSTRACT
Context and objective. Despite being established as a correlate of unfavorable outcome in acute stroke, little is known about the burden and associated risk factors of admission hyperglycemia in acute stroke in sub-Saharan Africa. The present study aimed to assess its frequency and associated risk factors in Congolese patients admitted in Intensive Care Units (ICUs) in the acute phase of stroke. Methods. A multicenter (6 ICUs) prospective cohort study including consecutive patients with acute stroke was undertaken from July 15th, 2017 to March 15th, 2018.The Glasgow Coma Scale helped to determine the severety of the disease at admission. Stress hyperglycemia was considered for a random blood glucose levels at admission ˃140 mg/dL in patients without type 2 diabetes mellitus (T2DM). Independent factors associated with admission hyperglycemia were assessed using logistic regression analysis. Results. Out of 194 patients (mean age 58.7±13.1 years; 64% males, 74.7% light to moderate stroke severity; 59% hemorrhagic stroke) enrolled, admission hyperglycemia was found in 106 (54.6%) of patients (mean age 60.1 ± 14.3 years; 67% men, 67% hypertension) with 77 (72.6%) and 29 (27.4 %) of them having stress and chronic hyperglycemia, respectively. Independent predictors of admission hyperglycemia were age [aOR 1.98; 95%CI 1.17-3.36), GCS < 8 (aOR 3.83; 95% CI 1.99-7.35) and diabetes (aOR 9.02; 95%CI 3.38-14.05). Conclusion. More than half of critically ill patients exhibit admission hyperglycemia with age, severity of stroke and known diabetes as its main associated risk factors
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Texto completo: Disponible Índice: AIM (África) Asunto principal: Admisión del Paciente / República Democrática del Congo / Factores de Riesgo / Accidente Cerebrovascular / Hiperglucemia / Unidades de Cuidados Intensivos Tipo de estudio: Ensayo Clínico Controlado / Estudio de etiología / Estudio observacional / Estudio pronóstico / Factores de riesgo País/Región como asunto: Africa Idioma: Inglés Revista: Ann. afr. méd. (En ligne) Año: 2020 Tipo del documento: Artículo

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Texto completo: Disponible Índice: AIM (África) Asunto principal: Admisión del Paciente / República Democrática del Congo / Factores de Riesgo / Accidente Cerebrovascular / Hiperglucemia / Unidades de Cuidados Intensivos Tipo de estudio: Ensayo Clínico Controlado / Estudio de etiología / Estudio observacional / Estudio pronóstico / Factores de riesgo País/Región como asunto: Africa Idioma: Inglés Revista: Ann. afr. méd. (En ligne) Año: 2020 Tipo del documento: Artículo