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Diagnostic de la tuberculose par immunocapture du bacille tuberculeux (sur billes magnetiques)
Chanteau, S; Marchal, G. Et Al; Rabe, O.
  • Chanteau, S; s.af
  • Marchal, G. Et Al; s.af
  • Rabe, O; s.af
Arch. inst. pasteur Madag ; 67(1-2): 37-40, 2001.
Artículo en Francés | AIM | ID: biblio-1259525
ABSTRACT
"Detection of Mycobacterium tuberculosis by use of immunocapture technique"" Tuberculosis is worldwide considered as a major health problem with high morbidity and mortality rates. Diagnosis of tuberculosis can be problematic. Microscopy; as the basic diagnostic method; stands inadequately alone due to a low sensitivity; and culture suffers from being time-consuming. A rapid; sensitive and simple diagnostic test; applicable in the field is therefore highly needed. A diagnostic method for the detection of M. tuberculosis by immunocapture technique has been developed using magnetic beads coated with polyclonal anti-M. tuberculosis. The detection of captured bacilli using biotinylated anti-APA monoclonal antibody (APA is a minor secreted antigen) was found more sensitive than microscopy. The results suggest that the development of a rapid strip test to detect major antigen could be a useful tool for the control of tuberculosis."
Asunto(s)
Texto completo: Disponible Índice: AIM (África) Asunto principal: Magnetismo / Mycobacterium tuberculosis / Antígenos Idioma: Francés Revista: Arch. inst. pasteur Madag Año: 2001 Tipo del documento: Artículo

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Texto completo: Disponible Índice: AIM (África) Asunto principal: Magnetismo / Mycobacterium tuberculosis / Antígenos Idioma: Francés Revista: Arch. inst. pasteur Madag Año: 2001 Tipo del documento: Artículo