Seroprevalence of Hepatitis B virus surface antigen, anti-hepatitis C virus antibody and their associated factors among mothers living in Harar, Eastern Ethiopia
Ethiop. med. j. (Online)
;
57(3): 119-127, 2019. tab
Artículo
en Inglés
| AIM
| ID: biblio-1262021
ABSTRACT
Background:
Hepatitis B virus (HBV) and Hepatitis C Virus (HCV) infections are major causes of acute and chronic liver disease and infection by these viruses during pregnancy is associated with maternal, fetal and neonatal health complications. Understanding the epidemiology of these viruses could be valuable to take appropriate preventive measures.Objective:
This study aims to determine the seroprevalence and associated factors of HBV and HCV infection among mothers living in Harar, Ethiopia. Materials andMethods:
A cross-sectional study was conducted among 461 mothers living in Harar, Eastern Ethiopia from March 1 May 30, 2017. The systematic random sampling method was used to select the study participants. Sociodemographic information was collected through face-to-face interviews using pretested structured questionnaires. Five millilitres of venous blood was collected from each study subject and HBsAg and anti-HCV levels in sera were tested using a sandwich third generation Enzyme-Linked Immunosorbent Assay (ELISA). Data was analysed by using Statistical Package for Social Sciences (SPSS) version 20.Result:
The seroprevalence rates for HBV and HCV infection were 5.9% and 1.1%, respectively. None of the mothers were co-infected with HBV and HCV. Among the potential risk factors, previous history of abortion (AOR =3.7 95%, CI 1.4-9.6) and multiple sexual exposures (AOR =10.6, 95% CI 4.0-27.9) were significant predictors of HBV infection.Conclusion:
This study determined that the prevalence of HBV and HCV infection among mothers was 5.9% and 1.1% respectively. History of abortion and history of multiple sexual partners were significantly associated with HBV infection. Health education programs on the mode of HBV and HCV transmission, high-risk behaviours and methods of preventions are recommended to raise awareness and reduce the spread of infection
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Índice:
AIM (África)
Asunto principal:
Virus de la Hepatitis B
/
Factores de Riesgo
/
Hepatitis C
/
Etiopía
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Investigación cualitativa
/
Factores de riesgo
País/Región como asunto:
Africa
Idioma:
Inglés
Revista:
Ethiop. med. j. (Online)
Año:
2019
Tipo del documento:
Artículo
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