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Sickle Cell Chronic Lung Disease among Young Adult Nigerians
Fawibe, A. E; Oluboyo, P. O; Salami, A. K.
  • Fawibe, A. E; s.af
  • Oluboyo, P. O; s.af
  • Salami, A. K; s.af
West Afr. j. med ; 29(1): 30-33, 2010.
Artículo en Inglés | AIM | ID: biblio-1273465
ABSTRACT

BACKGROUND:

Sickle cell chronic lung disease (SCLD) is often underappreciated by health care providers because its exact prevalence and methods of diagnosis have not been well studied.

OBJECTIVE:

To describe the pattern of SCLD among young adult Nigerians with sickle cell anaemia (SCA).

METHODS:

Ninety (43 males and 47 females) patients with SCA who were selected by balloting and 90 (54 males and 36 females) healthy subjects with normal adult haemoglobin were studied. Their ventilatory function test (spirometry and peak expiratory flow rates); radiological and electocardiographic parameters were obtained and analyzed for SCLD.

RESULTS:

Seventeen (18.9) of the patients had SCLD. Majority (94.1) of them were in stage1 disease; 5.9in stage two; and none in the more advanced stages3 and 4. The number of patients with SCLD increased with increasing age. SCLD was associated with more than five previous hospital admissions (82.4; OR=10.02; CI=4.51-22.22) and presence of symptoms suggesting previous acute chest syndrome (dyspnoea in 58.8; OR=33.33; CI=7.39-150.30; chest pain in 94.1; OR=81.33; CI= 9.83-672.85; cough in 47.1; OR=64.00; CI=7.15-572.60).

CONCLUSION:

SCLD may not be a rare event in Nigeria. Therefore efforts should be made to diagnose it in the early asymptomatic stage so as to offer effective intervention therapy to halt progression to the more disabling advanced stages
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Índice: AIM (África) Asunto principal: Adulto Joven / Anemia / Enfermedades Pulmonares Tipo de estudio: Factores de riesgo Idioma: Inglés Revista: West Afr. j. med Año: 2010 Tipo del documento: Artículo

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Índice: AIM (África) Asunto principal: Adulto Joven / Anemia / Enfermedades Pulmonares Tipo de estudio: Factores de riesgo Idioma: Inglés Revista: West Afr. j. med Año: 2010 Tipo del documento: Artículo