Interdisciplinary investigation of occurrence of diverticular disease among patients referred for barium enema and colonoscopy studies at Dr. George Mukhari Academic Hospital, Ga-Rankuwa, Pretoria, South Africa

ABSTRACT

Background: Diverticular disease (DD) is believed to be a disease which is prevalent in developed countries. Contrary to this belief, DD has been reported with an increasing trend in prevalence in Africa for the past four decades. Objectives: The objective of this study was to highlight the increasing trend of DD and to corroborate barium enema findings obtained from Diagnostic Radiology Department, with colonoscopy results from the Surgery Department at Dr. George Mukhari Academic Hospital. Methods: Results for barium enema and colonoscopy investigations of all the patients referred over a 1-year period were retrospectively reviewed by two independent research groups; each of these groups was unaware of the research carried out in the Departments of Diagnostic Radiology and Surgery. Data from the records were analyzed with the Statistical Package for the Social Sciences (IBM SPSS, version 22.0), New York, USA, version 22.0. Results: Barium enema results of 166 patients were evaluated for DD, and out of these, 129 patients (77.7%) were negative, while 37 patients (22.3%) (95% confidence interval = 19.07­25.50) were positive. A review of 384 colonoscopy results also revealed positive evidence for 47 patients (13.5%) (95% confidence interval = 10.30­17.50) for DD and 337 patients (86.5%) were negative. The findings of barium enema and colonoscopy investigative studies were similar for female preponderance, diffuse pattern of distribution of DD and the mean age of patients. Conclusion: The two studies corroborate each other and have produced the highest number of diagnostic yield for DD in one year, in Africa