Metagenomic next-generation sequencing (mNGS) for diagnostically challenging infectious diseases in patients with acute leukemia
Braz. j. infect. dis
;
25(2): 101548, 2021.
Artículo
en Inglés
| LILACS
| ID: biblio-1278574
ABSTRACT
ABSTRACT This report shows the contribution of next-generation metagenomic sequencing (mNGS) as an alternative to challenging diagnostic infection in immunosuppressed individuals. Herein, we report three acute leukemia patients who developed severe invasive infections due to different etiologies fungi, viruses, and protozoa. mNGS improved the diagnosis of the infections and provided the opportunity for adequate therapy. The mNGS is a hypothesis-free diagnostic platform, increasing potential in challenging diseases in hematological patients due to the extended diagnostic panel and the expedite access to the result.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Leucemia
/
Enfermedades Transmisibles
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Braz. j. infect. dis
Asunto de la revista:
Enfermedades Transmisibles
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Complexo Hospitalar de Niterói/BR
/
Universidade Federal do Rio de Janeiro/BR
/
Universidade de São Paulo/BR
Similares
MEDLINE
...
LILACS
LIS