Classification of fundus autofluorescence abnormal patterns in diabetic macular edema
Gac. méd. Méx
;
155(5): 458-462, Sep.-Oct. 2019. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1286543
ABSTRACT
Introduction: Patients with diabetic macular edema can develop fundus autofluorescence alterations; thus far, these alterations have been more widely studied with scanning or confocal laser systems. Objective: To describe and classify fundus autofluorescence abnormal patterns in patients with diabetic macular edema using the fundus autofluorescence system with a flash camera. Method: Observational, retrospective, cross-sectional, descriptive study. Fundus autofluorescence digital images of non-comparative cases with untreated diabetic macular edema, obtained and stored with a flash camera system, were assessed. Inter-observer variability was evaluated. Results: 37 eyes of 20 patients were included. Lens opacity was the most common cause of inadequate image quality. Five different fundus autofluorescence patterns were observed: decreased (13%), normal (40%), single-spot hyper-autofluorescent (17 %), multiple-spot hyper-autofluorescent (22 %) and plaque-like hyper-autofluorescent (8 %). The kappa coefficient was 0.906 (p = 0.000). Conclusions: Different fundus autofluorescence phenotypic patterns are observed with flash camera systems in patients with diabetic macular edema. A more accurate phenotypic classification could help establish prognostic factors for visual loss or for the design of clinical trials for diabetic macular edema.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Edema Macular
/
Retinopatía Diabética
/
Imagen Óptica
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio de prevalencia
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
México
Idioma:
Inglés
Revista:
Gac. méd. Méx
Asunto de la revista:
Medicina
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
México
Institución/País de afiliación:
Clínica David/MX
/
Hospital Civil de Guadalajara/MX
/
Hospital Dr. Luis Sánchez Bulnes/MX
/
Secretaría de Salud/MX
/
Universidad Anáhuac Norte/MX
Similares
MEDLINE
...
LILACS
LIS