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Prevalence of Hashimoto's thyroiditis in psoriasis patients
Valduga, Júlia Amanda Guzatti; Rebeiko, Leticia Boçon; Skare, Thelma Larocca.
  • Valduga, Júlia Amanda Guzatti; Hospital Evangélico Mackenzie. Curitiba. BR
  • Rebeiko, Leticia Boçon; Hospital Evangélico Mackenzie. Curitiba. BR
  • Skare, Thelma Larocca; Hospital Evangélico Mackenzie. Curitiba. BR
Rev. Assoc. Med. Bras. (1992) ; 67(1): 52-57, Jan. 2021. tab, graf
Artículo en Inglés | LILACS | ID: biblio-1287780
ABSTRACT
SUMMARY

OBJECTIVE:

To study the prevalence of Hashimoto's Thyroiditis in a sample of psoriasis patients.

METHODS:

Cross-sectional observational study of 120 individuals (60 with psoriasis and 60 control subjects) paired by gender and age for thyroid function (thyroid stimulating hormone, free T4), antithyroperoxidase and antithyroglobulin tests and physical examination. Psoriasis Area and Severity Index and Nail Psoriasis Severity Index were evaluated simultaneously. Epidemiological, clinical and treatment data was collected from medical records. Patients with documented hypothyroidism and/or goiter associated with positive antithyroperoxidase antibody were considered to have Hashimoto's Thyroiditis.

RESULTS:

The prevalence of Hashimoto's Thyroiditis in the group with psoriasis was 21.6%; in the control group, it was 4/60 (6.6%) with p=0.03 (OR=3.8; 95%CI 1.18-12.6). In the group of patients with psoriasis, Hashimoto's Thyroiditis was more common in women (p=0.002) and less common in those who had polyarticular arthropathic psoriasis (p=0.05) and plaque psoriasis (p=0.005). A logistic regression showed that the only independent variable associated with Hashimoto's thyroiditis was plaque psoriasis.

CONCLUSIONS:

There is a high prevalence of Hashimoto's Thyroiditis in psoriatic patients, especially in women. Hashimoto's Thyroiditis is less common in patients with the plaque form of psoriasis.
Asunto(s)


Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Psoriasis / Enfermedad de Hashimoto / Hipotiroidismo Tipo de estudio: Estudio observacional / Estudio de prevalencia / Factores de riesgo Límite: Femenino / Humanos Idioma: Inglés Revista: Rev. Assoc. Med. Bras. (1992) Año: 2021 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Hospital Evangélico Mackenzie/BR

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Psoriasis / Enfermedad de Hashimoto / Hipotiroidismo Tipo de estudio: Estudio observacional / Estudio de prevalencia / Factores de riesgo Límite: Femenino / Humanos Idioma: Inglés Revista: Rev. Assoc. Med. Bras. (1992) Año: 2021 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Hospital Evangélico Mackenzie/BR