Association of bone mineral density with chronic obstructive pulmonary disease in postmenopausal women
Rev. invest. clín
;
71(3): 204-210, May.-Jun. 2019. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1289688
ABSTRACT
Abstract Background Osteoporosis (OP) is common in patients with chronic obstructive pulmonary disease (COPD). The relationship between OP and COPD has been primarily studied in male patients, and few reports are available in postmenopausal women. Objective The purpose of this study was to investigate the association between bone mineral density (BMD) and COPD in postmenopausal women. Methods This cross-sectional study included 133 clinically stable female ex-smokers with confirmed COPD, and 31 age-matched ex-smoker female controls. We analyzed groups according to their airway obstruction category. BMD was measured on dual-energy X-ray absorptiometry images of the left femoral neck. Results Patients with COPD had lower T-scores and higher prevalence of osteopenia/OP than the control group. In the COPD group, the airway obstruction category was significantly associated with the T-score after adjustment for confounders. Multivariate logistic regression analysis showed COPD was an independent marker for increased risk of osteopenia/OP in postmenopausal women. Conclusions COPD and airway obstruction category were strongly related to BMD. Postmenopausal women with COPD, especially those with severe airway obstruction, had a higher prevalence rate and a higher risk of osteopenia and OP than female controls without COPD.
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Índice:
LILACS (Américas)
Asunto principal:
Densidad Ósea
/
Osteoporosis Posmenopáusica
/
Posmenopausia
/
Enfermedad Pulmonar Obstructiva Crónica
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio de prevalencia
/
Factores de riesgo
Límite:
Anciano
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Rev. invest. clín
Asunto de la revista:
Medicina
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
China
Institución/País de afiliación:
Peoples Hospital of Xinjiang Uygur Autonomous Region/CN
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