Comparison of two commercial tests (Immy vs. Dynamiker) for cryptococcal capsular antigen
Rev. Soc. Bras. Med. Trop
;
54: e03072021, 2021. tab
Artículo
en Inglés
| LILACS
| ID: biblio-1340825
ABSTRACT
Abstract INTRODUCTION Lateral flow assay is an advanced method useful in the early diagnosis of cryptococcal meningitis. We aimed to compare two commercial tests for cryptococcal capsular antigen in the sera of asymptomatic patients with human immunodeficiency virus in Barranquilla, Colombia. METHODS Thawed (n=162) previously collected serums (2016-2019) were processed using IMMY and Dynamiker cryptococcal antigen lateral flow assay. RESULTS Compared to IMMY's results, Dynamiker's sensitivity, specificity, positive predictive value, negative predictive value, and kappa index were 100%, 89.9%, 48.3%, 100.0%, and 0.61, respectively. CONCLUSIONS The Dynamiker test had excellent sensitivity, acceptable specificity, and a low detection threshold for cryptococcal antigen in the tested samples.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Infecciones por VIH
/
Meningitis Criptocócica
/
Cryptococcus
Tipo de estudio:
Estudio pronóstico
/
Estudio de tamizaje
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
Colombia
Institución/País de afiliación:
Instituto Nacional de Salud/CO
/
Universidad Metropolitana/CO
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