Congenital Heart Disesase: A Retrospective Analysis from a Tertiary Referral Centre in Portugal
Int. j. cardiovasc. sci. (Impr.)
;
34(5,supl.1): 105-113, Nov. 2021. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1346344
ABSTRACT
Abstract Background:
Congenital heart disease is the leading cause of mortality among all congenital malformations.Objectives:
To evaluate the incidence of congenital heart diseases in a central maternity hospital in Portugal from January 2003 to December 2018 and to determine survival in the first year of life.Methods:
Retrospective analysis of newborns diagnosed with congenital heart diseases within 72 hours after birth. Malformations were divided according to pathophysiology. Cumulative survival analysis was performed by the Kaplan-Meier test. Stastical significance was set at p <0.05.Results:
A total of 297 newborns with cardiac malformation was recorded among 47,198 live births (incidence of 61000), 16% associated with extra-cardiac disease. The most frequent congenital heart diseases were left-to-right shunt lesions (n = 216), followed by cyanotic (n = 41), acyanotic obstructive (n = 31) and miscellaneous (n = 9). Seventy (24%) patients had prenatal diagnosis, 88% of them cyanotic defects, and a positive association was found between prenatal diagnosis and mortality (p <0.001). Coarctation of the aorta was associated with gestational diabetes (p = 0.014). Atrial septal defect was more common in females (p = 0.02). Mortality rate due to heart disease was 3.4%. Patients with cyanotic disease, 99%, 97%, 97%, respectively, for patients with left-to-right shunt lesions, and 97%, 97%,97% for those with obstructive lesion cases.Conclusion:
The incidence of congenital heart disease was 61000, mostly left-to-right shunt lesions. Heart disease accounted for only half of deaths, and cyanotic diseases have a high nonspecific mortality rate.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Cardiopatías Congénitas
Tipo de estudio:
Estudio de incidencia
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Femenino
/
Humanos
/
Masculino
/
Recién Nacido
País/Región como asunto:
Europa
Idioma:
Inglés
Revista:
Int. j. cardiovasc. sci. (Impr.)
Asunto de la revista:
Cardiología
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
Portugal
Institución/País de afiliación:
Centro Hospitalar e Universitário de Coimbra/PT
Similares
MEDLINE
...
LILACS
LIS