Cerebrospinal Fluid Infection with External Ventricular Drainage: Analysis of the Risk Factors in 110 Patients of a Single Institution
Arq. bras. neurocir
;
39(3): 161-169, 15/09/2020.
Artículo
en Inglés
| LILACS
| ID: biblio-1362437
ABSTRACT
Objectives External ventricular drainage (EVD) is extensively used in the neurosurgical practice with the purpose of monitoring the intracranial pressure and draining the cerebrospinal fluid (CSF). Despite its remarkable benefits, the technique is not devoid of risks, notably infections, which have been reported in up to 45% of the cases. Methods A retrospective analysis of the main risk factors for CSF infection in neurosurgical patients submitted to EVD at a single institution. We recorded and submitted to statistical comparison every risk factor for CSF infection present or absent in each of the 110 EVD patients enrolled, 53 males and 57 females, with an average age of 52.9 years, with different underlying neurosurgical conditions. Results Infection of the CSF occurred in 32 patients (29%). The rate of mortality related to CSF infection was of 18.7% (6 of 32). The risk factors that showed statistical significance for CSF infection in this series were: emergency surgery; length of stay at the intensive care unit (UCI); duration of the EVD; parenchymal and/or intraventricular hemorrhage; simultaneous infections; time of bladder catheterization; and the use of non-disposable adhesive drapes as part of the preparation of the wound area. Conclusions Infection of the CSF in patients submitted to EVD is multifactorial and a challenge in terms of prevention. Further studies proposing scores with blended risk factors may be useful to prevent and reduce the morbidity and mortality associated with CSF infection.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Infecciones del Sistema Nervioso Central
/
Derivación Ventriculoperitoneal
/
Pérdida de Líquido Cefalorraquídeo
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Factores de riesgo
Idioma:
Inglés
Revista:
Arq. bras. neurocir
Asunto de la revista:
Cirurgia
/
Neurocirugía
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Department of Surgery, Hospital de Clínicas, Universidade Federal do Paraná (UFPR)/BR
/
Programa de Pós-Graduação em Clínica Cirúrgica, Universidade Federal do Paraná (UFPR)/BR
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