Deep Brain Stimulation for the Treatment of Juvenile Parkinsonism: Case Report
Arq. bras. neurocir
;
38(2): 124-127, 15/06/2019.
Artículo
en Inglés
| LILACS
| ID: biblio-1362598
ABSTRACT
Juvenile parkinsonism (JP) is characterized by the clinical manifestation of Parkinson syndrome before the age of 21 years old. This entity is often associated with genetic mutations. After all the possibilities of clinical treatment have been exhausted, surgical treatment is recommended, performed via deep brain stimulation (DBS) in the subthalamic nucleus (STN) or in the internal segment of the globus pallidus (GPi). The present study aimed to report the case of a patient with JP who underwent DBS in the STN with good clinical response. Neuromodulation via DBS is an option for the treatment of JP. However, since this entity is very rare, and even more peculiar when treated surgically, more studies are necessary to evaluate DBS used to control refractory manifestations and levodopa-induced dyskinesia, as well as surgical complications that may occur, aiming to gather more knowledge of the surgical management of JP. Despite the dysarthria after the DBS, the patient presented a satisfactory response regarding the symptoms, corroborated by the Parkinson's Disease Questionnaire (PDQ-39) score, which was 61.19% before the procedure, and decreased to 21.05% 14 months after the DBS.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Núcleo Subtalámico
/
Trastornos Parkinsonianos
/
Estimulación Encefálica Profunda
/
Disartria
Límite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Arq. bras. neurocir
Asunto de la revista:
Cirurgia
/
Neurocirugía
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
School of Medical, Pharmaceutical, and Biomedical Sciences, Pontifícia Universidade Católica de Goiás/BR
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