Trigeminal Cave Brain Metastasis from Prostate Adenocarcinoma: Case Report and Review of the Literature
Arq. bras. neurocir
;
37(4): 330-333, 15/12/2018.
Artículo
en Inglés
| LILACS
| ID: biblio-1362652
ABSTRACT
The present study presents the case of a 66-year-old patient diagnosed with prostate adenocarcinoma 4 years earlier and treated with prostatectomy, radiotherapy, chemotherapy and hormonetherapy but still displaying high prostate-specific antigen (PSA) levels. The patient complaints were double vision and headaches. Upon physical examination, he displayed 6th cranial nerve paresis and 5th cranial nerve paresthesia. Amagnetic resonance imaging (MRI) exam was performed, which revealed a mass on the right trigeminal cave. The patient underwent surgical removal of the tumor, and the pathological analysis of the specimen established metastatic prostate cancer as the diagnosis. Brainmetastases fromprostate cancer are extremely rare and mark advanced disease, with immune system failure and blood-brain barrier breach. Prostate-specific antigen levels do not correlate with the possibility of metastatic disease. Prostate adenocarcinoma is the histologic typemost commonly associated with brainmetastases,with themeninges being more frequently affected, followed by the brain parenchyma. The neurological symptoms more often displayed are non-focal, such as headaches and mental confusion. Surgery associated with radiotherapy is the most validated treatment.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Neoplasias de la Próstata
/
Nervio Trigémino
/
Adenocarcinoma
/
Antígeno Prostático Específico
Tipo de estudio:
Estudio diagnóstico
Límite:
Anciano
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Arq. bras. neurocir
Asunto de la revista:
Cirurgia
/
Neurocirugía
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Department of Neurosurgery, Hospital da Cidade de Passo Fundo/BR
/
Department of Oncology, Hospital da Cidade de Passo Fundo/BR
/
Faculty of Medicine, Centro Universitário Assis Gurgacz/BR
/
Faculty of Medicine, Universidade de Passo Fundo/BR
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