A Randomized Clinical Trial on Therapeutic Effects of Myrtus communis L. Cream on Chronic Skin Lesions and Quality of Life of Sulfur Mustard-exposed Veterans
Braz. arch. biol. technol
;
65: e22210268, 2022. tab
Artículo
en Inglés
| LILACS
| ID: biblio-1364472
ABSTRACT
Abstract: Sulfur mustard is one of the chemical warfare agent. It rapidly reacts with the cutaneous tissues and other tissues, leading to various devastating long-term effects on human health. Mustard-exposed veterans suffer from its chronic skin problems, including itching, burning sensation, and eczema. We aimed to evaluate the protective effects of Myrtus communis L. (myrtle) on chronic skin lesions and quality of life of sulfur mustard-exposed veterans. In this randomized, double-blind clinical trial, 60 sulfur mustard-exposed patients were evaluated. Thirty patients received myrtle essence 5% cream (case group) and 30 patients received Eucerin cream (placebo group) twice in a day for one month. Then, We assessed the chronic skin problems and itching-related parameters (such as the itching time, severity, distribution, frequency, and calculated itching score), duration of sleep, number of waking up at night, and quality of life in the both groups. Our analysis of data revealed that application of myrtle cream effectively decreased skin problems including; itching and burning sensation. Additionally, myrtle markedly decreased skin lesion symptoms such as excoriation in the case group as compared with before treatment. Noticeably, myrtle cream significantly improved quality of life of the patients in the case group. The present study provides more in-depth information regarding the protective role of myrtle on the sulfur mustard-induces skin complication. Also, myrtle effectively improved quality of life of the sulfur mustard-exposed veterans.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Enfermedades de la Piel
/
Extractos Vegetales
/
Sustancias para la Guerra Química
/
Myrtus communis
/
Fitoterapia
/
Gas Mostaza
Tipo de estudio:
Ensayo Clínico Controlado
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Braz. arch. biol. technol
Asunto de la revista:
Biologia
Año:
2022
Tipo del documento:
Artículo
País de afiliación:
Irán
Institución/País de afiliación:
Baqiyatallah University of Medical Sciences/IR
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