Análisis de inmunogenicidad y perfil de seguridad de vacunas contra el SARS-CoV-2 en ensayos clínicos de fase I/II / Immunogenicity and safety profile analysis of SARS-CoV-2 vaccines in phase I/II clinical trials
Rev. méd. Maule
;
35(1): 18-24, oct. 2020. tab
Artículo
en Español
| LILACS
| ID: biblio-1366379
ABSTRACT
The development of an effective vaccine against SARSCoV-2 has turned into a global priority in order to stop the advance of this ongoing COVID-19 pandemic. To date there are 25 candidate vaccines currently in a clinical trial stage, 3 of which have been subjected to phase I/II preliminary reports (ChAdOx1 nCoV-19, BNT162b1 and mRNA-1273). These vaccines have demonstrated to elicit robust cellular and humoral immune responses when compared to convalescent patients serum samples and have shown an acceptable safety profile with no reported severe side effects. Here we discuss the reported evidence regarding these vaccines.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Vacunas Virales
/
Pandemias
/
COVID-19
Tipo de estudio:
Ensayo Clínico Controlado
Límite:
Humanos
Idioma:
Español
Revista:
Rev. méd. Maule
Asunto de la revista:
Medicina
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
Chile
Institución/País de afiliación:
Hospital Regional de Talca/CL
/
Universidad Católica del Maule/CL
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