Consumption of mate Ilex paraguariensis: a folk beverage with antioxidant power against myocardial ischemic injury
Acta sci., Health sci
;
44: e55845, Jan. 14, 2022.
Artículo
en Inglés
| LILACS
| ID: biblio-1366721
ABSTRACT
The effects of the aqueous extract of Ilex paraguariensis (Ip)and the flavonoid quercetin were tested during the induction of in vivomyocardial ischemia/ reperfusion in Rattus norvegicus. The antioxidant power of the extract and quercetin were chemically determined. The experimental groups were control, ischemia/reperfusion induction, Iporal treatment, Iporal treatment and ischemia /reperfusion, quercetin oral treatment, and quercetin oral treatment and ischemia/reperfusion. Rats were anesthetized with sodium thiopental and xylazine via intraperitoneal injection and subsequently underwent 15 minutes of ischemia followed by 15 minutes of reperfusion. Ischemia was promoted by tying the left anterior descending coronary artery. Areas of risk and infarction were stained by intravenous Evans blue and triphenyl tetrazolium chloride. Reactive oxygen species (ROS), antioxidant capacity against peroxylradicals, and lipid peroxidation of the myocardium were quantified. A significant reduction in areas of risk and infarction was detected in the ischemic myocardium treated with Ipand quercetin; ROS generation and lipid peroxidation were significantly reduced, and the antioxidant capacity was elevated. Oral administration of Ippromoted antioxidant benefits in the myocardium during ischemia and reperfusion, which reduced infarction. We suggest that Mate (a hot drink made from steeped dried leaves of Ip) consumption is a potential cardioprotective habit of indigenous people from southern South American countries, which must be better understood scientifically and ethnographically.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Flavonoides
/
Ilex paraguariensis
/
Isquemia
/
Antioxidantes
Tipo de estudio:
Estudios de evaluación
/
Investigación cualitativa
Límite:
Animales
Idioma:
Inglés
Revista:
Acta sci., Health sci
Asunto de la revista:
Medicina
/
Sa£de P£blica
Año:
2022
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal de Pelotas/BR
/
Universidade Federal do Rio Grande/BR
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