Encefalopatía subaguda en una paciente con policondritis recidivante: caso clínico / Subacute encephalopathy associated with relapsing polychondritis: report of one case
Rev. méd. Chile
;
149(7): 1085-1089, jul. 2021. ilus
Artículo
en Español
| LILACS
| ID: biblio-1389558
ABSTRACT
Relapsing polychondritis (RP) is a rare multisystemic autoimmune disorder characterized by the inflammation and destruction of cartilages, with preference for auricular, nasal and laryngotracheal cartilages. RP may also affect proteoglycan-rich structures, such as, blood vessels, eyes, kidneys, and heart. The central nervous system (CNS) is involved in less than 3% of patients. We report a 32-year-old female with RP associated with a progressive subacute encephalopathy characterized by behavioral disturbances, auditory and visual hallucinations. The EEG showed generalized slow activity and a mononuclear pleocytosis with increased protein was found in the cerebrospinal fluid. The brain magnetic resonance imaging showed multiple supra and infratentorial nodular inflammatory lesions. After initiating treatment with corticosteroids and cyclophosphamide, a significant improvement in chondritis and neurological status was observed.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Policondritis Recurrente
/
Encefalopatías
Tipo de estudio:
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2021
Tipo del documento:
Artículo
País de afiliación:
Chile
Institución/País de afiliación:
Hospital del Salvador/CL
/
Universidad de Chile/CL
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