Human enteroviral infection in fibromyalgia: a case-control blinded study
Rev. Assoc. Med. Bras. (1992)
;
68(7): 945-947, July 2022. tab
Artículo
en Inglés
|
LILACS-Express
| LILACS
| ID: biblio-1394577
ABSTRACT
SUMMARY OBJECTIVE:
This study aimed to test the hypothesis that fibromyalgia is associated with a human enteroviral infection.METHODS:
Venous peripheral blood samples from 27 patients fulfilling the American College of Rheumatology revised diagnostic criteria for fibromyalgia and from 26 age- and sex-matched controls, who underwent immunofluorescence assays for coxsackievirus A7 IgG, coxsackievirus B1 IgG, coxsackievirus A7 IgA, coxsackievirus B1 IgA, echovirus IgG, and echovirus IgA. These immunological tests were performed blind to group status.RESULTS:
There were no significant differences between the patient and control groups in respect of positive results for coxsackievirus A7 IgG (p=0.467), coxsackievirus B1 IgG (p=0.491), coxsackievirus A7 IgA (p=0.586), coxsackievirus B1 IgA (p=0.467), echovirus IgG (p=0.236), and echovirus IgA (p=1).CONCLUSIONS:
The results of this systematic study do not support the hypothesis that fibromyalgia is associated with infection by a human enterovirus.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Tipo de estudio:
Estudio observacional
Idioma:
Inglés
Revista:
Rev. Assoc. Med. Bras. (1992)
Año:
2022
Tipo del documento:
Artículo
País de afiliación:
Alemania
/
Reino Unido
Institución/País de afiliación:
ArminLabs GmbH/DE
/
University of Southampton/GB
/
University of Winchester/GB
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